Sarcoma

New sarcoma research reported from Niigata University

Published in Surgery Litigation and Law Weekly, July 10th, 2009

"Alveolar soft part sarcoma (ASPS) is a distinct, rare soft tissue tumor with an unknown histogenesis and a tendency for late widespread metastases to lung, bone, and brain. It is now clear that they are caused by a specific unbalanced translocation, der(17)t(X;17)(p11;q25), which results in the formation of all ASPSCR1-TFE3 (alias ASPL-TFE3) fusion gene," researchers in Niigata, Japan report.

"The rearrangement results; ill the expression of chimeric transcripts, which can be identified by means of reverse transcriptase-polymerase chain reaction (RT-PCR). We investigated the histogenesis of ASPS and attempted to detect Circulating ASPS tumor cells in peripheral blood....

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Source: Surgery Litigation and Law Weekly (2009-07-10)

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