Chronic Obstructive Pulmonary Disease

Reports from J. Marincorral and colleagues advance knowledge in chronic obstructive pulmonary disease

Published in Surgery Litigation and Law Weekly, August 14th, 2009

"In the diaphragms of chronic obstructive pulmonary disease (COPD) patients, the nature of oxidatively modified proteins and superoxide anion production were explored. Diaphragm specimens were obtained through thoracotomy because of localised lung lesions in COPD patients (16 severe and eight moderate) and 10 control subjects," scientists writing in the European Respiratory Journal report.

"Lung and respiratory muscle functions were evaluated. Oxidised proteins were identified using immunoblotting and mass spectrometry. Protein and activity levels of the identified proteins were determined using immunoblotting and activity assays. Lucigenin-derived...

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Source: Surgery Litigation and Law Weekly (2009-08-14)

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