Lung Cancer Therapy
Studies from Sapporo Medical University, Department of Pathology update current data on lung cancer therapy
Published in Surgery Litigation and Law Weekly, September 11th, 2009
Researchers detail in 'Novel spliced form of a lens protein as a novel lung cancer antigen, Lengsin splicing variant 4,' new data in lung cancer. "A glutamine synthetase I family protein, Lengsin, was previously identified as a novel lens-specific transcript in the vertebrate eye. In this report, we show for the first time that Lengsin is a novel tumor-associated antigen expressed ectopically in lung cancer," investigators in Sapporo, Japan report.
"Interestingly, a novel spliced form of human Lengsin termed 'splicing variant 4', gaining exon 3 that codes extra 63 amino acids, is the dominant transcript form in lung cancer cells. Lengsin mRNA could be detected in 7 of...
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