Bone Morphogenetic Protein
Research on bone morphogenetic protein reported by B.S. Miguel et al
Published in Surgery Litigation and Law Weekly, December 4th, 2009
According to recent research from Zurich, Switzerland, "In medicine, N-methyl pyrrolidone (NMP) has a long track record as a constituent in medical devices approved by the Food and Drug Administration and thus can be considered as a safe and biologically inactive small chemical. In the present study, we report on the newly discovered pharmaceutical property of NMP in enhancing bone regeneration in a rabbit calvarial defect model in vivo."
"At the cellular level, the pharmaceutical effect of NMP was confirmed, in particular, in combination with bone morphogenetic protein (BMP)-2, because NMP increased early and late markers for maturation of preosteoblasts and human bone...
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