Life Sciences
Research on life sciences described by scientists at University of British Columbia, Department of Surgery
Published in Surgery Litigation and Law Weekly, March 26th, 2010
Data detailed in 'Keratinocyte-releasable factors increased the expression of MMP1 and MMP3 in co-cultured fibroblasts under both 2D and 3D culture conditions' have been presented. "Matrix metalloproteinases (MMPs) are key elements in extracellular matrix (ECM) degradation and scar remodeling during the wound-healing process. Our previous data revealed that keratinocyte-releasable factors significantly increased the expression of fibroblast MMPs in monolayer-cultured fibroblasts," investigators in Canada report.
"In this study, we analyzed the differences in the MMP expressions of fibroblasts in a three-dimensional fibroblast-populated collagen gel (3D FPCG) from that...
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