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Screening

BCG Vaccination Not Good Indicator of False-Positives

Published in TB and Outbreaks Week, May 15th, 1995

Attributing a "positive" Mantoux response to past BCG vaccination may be encouraging a false sense of security in contacts recently exposed to infectious tuberculosis (TB), according to a study from Ireland.

Routine screening methods to detect TB at an early stage have remained largely unchanged throughout the century. Tuberculin sensitivity continues to be used as a key indicator of TB infection.

"The interpretation of tuberculin sensitivity in the light of previous Bacillus Calmette-Guerin vaccination can pose a diagnostic dilemma," researcher H. Johnson and colleagues wrote ("Tuberculin Sensitivity and the BCG Scar in Tuberculosis Contacts,"...

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