"Biosynthesis and Polymerization of Darabinose in Mycobacteria."

According to an abstract presented by the authors to the Molecular Mechanisms in Tuberculosis Keystone Symposium, held February 19-25, 1995, in Tamarron, Colorado, "D-Arabinose (ara) is a major sugar of mycobacteria since it is found in the cell wall arabinogalactans and arabinomannans of these organisms. D-ara is an unusual component of complex carbohydrates, and only occurs in mycobacteria and a few related bacteria, and in some lower eucaryotes. However, it is not found in humans. Thus, steps in the biosynthesis or polymerization of D-ara should be excellent target sites for chemotherapy, assuming that the arabinogalactan and/or arabinomannan are essential to the viability of these...

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