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Prognosis

High Number of Autoantibodies Suggests TB Susceptibility

Published in TB and Outbreaks Week, May 29th, 1995

The finding of a high level of autoantibodies during the early phase of mycobacterial infection reflects host susceptibility to the infectious agent.

Environmental factors, infectious agents in particular, have been implicated in the triggering of autoantibody production in the host. Mycobacteria are among the microorganisms that are known to cause significant enhancement in autoantibodies during the first weeks of infection.

"The degree of mycobacteria-induced autoantibody production varies widely in different hosts, which has suggested that the phenomenon depends on the host genetic make-up," researcher A. Bras et al. wrote ("Mycobacteria-Induced...

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