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Diagnostics - Measurement of Complexed IgG

"Characterization of Mycobacterial Antigens and Antibodies in Circulating Immune Complexes from Pulmonary Tuberculosis."

Published in TB and Outbreaks Week, June 19th, 1995

According to the authors' abstract of an article published in Journal of Laboratory and Clinical Medicine, "Circulating immune complexes (CICs) in serum samples from patients with pulmonary tuberculosis (bacteriologically positive [S+C+] and bacteriologically negative [S-C-]) and controls (NHC) have been measured by using C1q binding assay (C1qBA) and 3.5% polyethylene glycol precipitation and measurement of absorbance at 280 nm (PEG-OD 280). Although C1qBA did not show any difference between tuberculous and normal serum samples, PEG-OD 280 was significantly elevated in tuberculous samples. The effect of chemotherapy on CIC levels was studied. During the treatment, initially (for up to...

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