Published in TB and Outbreaks Week, July 10th, 1995
Macrophages play a significant role in cell-mediated immune responses to mycobacterial infections. Through a series of evasive mechanisms mycobacteria effectively overcome destruction by host defenses. These include interference with the production of oxygen metabolites, inhibition of degranulation and phagosome-lysosome function, and an inference with macrophage activation.
"Because of such inhibitory effects of macrophages, it is conceivable that mycobacteria could negatively influence antigen presentation by...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB and Outbreaks Week
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.