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Testing

Colorimetic Assay Useful for TB Drug Susceptibility

Published in TB and Outbreaks Week, September 4th, 1995

The colorimetric method is a rapid, quantitative, nonradiometric approach to determining the antimicrobial susceptibility of Mycobacterium tuberculosis, according to a University of California report.

Determining the minimum inhibitory concentration (MIC) of antituberculosis agents is a time consuming process. The commonly used agar proportion method for mycobacterial susceptibility testing requires a three-week period of incubation, and the BACTEC radiometric susceptibility method takes from five to ten days. This later method requires the use of radioisotopes and is generally costly to perform.

In this report researcher David M. Yajko and...

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