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Clinical Definition

"Clinical Features and Serum Beta(2)-Microglobulin Levels in HIV-1 Positive and Negative Tanzanian Patients with Tuberculosis."

Published in TB and Outbreaks Week, September 11th, 1995

According to the authors' abstract of an article published in International Journal of STD & AIDS, "Serum beta(2)-microglobulin (beta(2)M) rises in the later stages of HIV disease and has therefore been used to monitor progression to AIDS. However, little work has been done on patients co-infected with HIV and tuberculosis. We studied clinical features and serum beta(2)-M in 35 Tanzanian patients treated for pulmonary tuberculosis (9 HIV-positive, 26 HIV-negative). The provisional WHO clinical definition of AIDS for use in Africa was fulfilled by 89% of the HIV-positive and 65% of the HIV-negative patients. Median serum beta(2)-M on admission was slightly higher in HIV-positive (3.17...

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