"Tuberculosis after Isoniazid Chemoprophylaxis in HIV Infected Patients: A Warning for Isoniazid Resistance."

According to an abstract submitted by the author to the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy, sponsored by the American Society for Microbiology, held September 17-20, 1995, in San Francisco, California, "Objective: To evaluate the long-term protection conferred by isoniazid against tuberculosis in patients co-infected with HIV and M. tuberculosis. Patients and Methods: A group of 27 HIV-infected patients who were PPD-positive and who received isoniazid (9-12 months) were followed for development of clinically and/or microbiologically documented tuberculosis. Patients were followed until development of tuberculosis, death, or the...

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