Epidemiology (TB)
"RFLP Analysis of the Mycobacterium tuberculosis Complex in Kwazulu-Natal, South Africa."
Published in TB and Outbreaks Week, November 6th, 1995
According to an abstract submitted by the authors to The Lancet Conference 'The Challenge of Tuberculosis', held September 14-15, 1995, in Washington, D.C., "Restriction fragment length polymorphism (RFLP) analysis was used to investigate the pattern of transmission of TB within a rural population in Hlabisa (an area in KwaZulu Natal), to determine whether RFLP patterns could be useful in predicting drug resistance profiles and to determine the role of exogenous reinfection in patients on treatment in a TB hospital. Horse-radish peroxidase labelled IS6110 was used as a probe to hybridise with PvuII digested chromosomal DNA. IS6110 containing fragments were detected by means of...
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