"A Species-Specific Nucleotide Sequence of Mycobacterium tuberculosis Encodes a Protein that Exhibits Hemolytic Activity When Expressed in Escherichia coli."

According to the authors' abstract of an article published in Infection and Immunity, "Species-specific proteins may be implicated in the unique pathogenic mechanisms characteristic of Mycobacterium tuberculosis. In previous studies, a 3.0-kb species-specific DNA fragment of M. tuberculosis was identified (C.A. Parra, L.P. Londono, P. del Portillo, and M.E. Patarroyo, Infect. Immun. 59:3411-3417, 1991). The nucleotide sequence of this 3.0-kb fragment has been obtained. This sequence was shown to contain two open reading frames (ORFs) whose putative gene products share 68.9% identity between each other. The major ORF shows 57.8% similarity with PLC-N and 53.2% similarity...

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