Animal Models

Mouse Model Useful for Determining TB Pathology

Published in TB and Outbreaks Week, December 25th, 1995

A murine study suggests that Mycobacterium tuberculosis is far more virulent when given by the respiratory route than by the intravenous route.

Researcher Robert J. North of New York's Trudeau Institute earlier reported that intravenous inoculation of mice with M. tuberculosis results in a slowly progressive infection in the lungs, despite the acquisition of systemic host immunity capable of resolving infection in the liver, spleen and kidneys.

"The present study was undertaken to determine whether the peculiar susceptibility of the lungs to M. tuberculosis infection is even more obvious in mice infected via the respiratory...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of TB and Outbreaks Week

Source: TB and Outbreaks Week (1995-12-25)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry