Pathogenesis

M. tb Replicates within Type II Alveolar Cells.

Published in TB and Outbreaks Week, May 6th, 1996

The invasion of alveolar epithelial cells may be associated with the pathogenesis of lung infection in Mycobacterium tuberculosis, according to a report from California.

Researcher Luiz E. Bermudex and colleagues of San Francisco's Kuzell Institute for Arthritis and Infectious Diseases found that M. tuberculosis is capable of invading type II alveolar epithelial cells.

"M. tuberculosis can enter an alveolar epithelial cell line by both microfilament- and microtubule-dependent pathways by using integrins as receptors," they wrote ("Mycobacterium tuberculosis Invades and Replicates with Type II Alveolar Cells," Infection and...

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Source: TB and Outbreaks Week (1996-05-06)

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