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Transmission

"Evaluation of Tuberculosis Transmission in a Community by 1 Year of Systematic Typing of Mycobacterium tuberculosis Clinical Isolates."

Published in TB and Outbreaks Week, May 27th, 1996

According to the authors' abstract of an article published in Journal of Clinical Microbiology, "Interhuman transmission of Mycobacterium tuberculosis was investigated by using molecular typing, including restriction fragment length polymorphism with probes IS6110, DR (direct repeat) and PGRS (polymorphic GC-rich sequence) and a PCR method using the inverted repeat sequences of IS6110 as primers. From 105 patients hospitalized for tuberculosis during a 1-year survey In three hospitals in Paris, France, 111 isolates were collected and analyzed. Eighty-eight patients were infected with genetically different isolates, demonstrating the clonal heterogeneity of M. tuberculosis...

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