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Diagnostics

IgG Detection Can Aid in Tuberculous Meningitis Detection

Published in TB and Outbreaks Week, June 24th, 1996

The detection of mycobacterial immune complexes (IgG) along with anti-mycobacterial antibodies can aid in the diagnosis of most cases of tuberculous meningitis, according to a report from India.

The diagnosis of tuberculous meningitis remains complicated despite many recent technological developments. The severity of the disease can be highlighted by high mortality (up to 45 percent), especially in the young. The low culture positivity for Mycobacterium tuberculosis in cerebrospinal fluid (CSF) has led to the increased use of immunoassays in the diagnosis of the disease.

The conventional immunoassays for the diagnosis of pulmonary or...

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