Pathogenesis
IL-4 Involved in Down-Regulation of Mycobacterial Induced IL-1(beta)
Published in TB and Outbreaks Week, June 24th, 1996
"Further studies are needed to establish the relevance of IL-4 in the pathogenesis of disease due to Mycobacterium tuberculosis, especially when mycobacteria induces a predominantly Th2 cytokine profile which could aggravate the mycobacterial infection," researcher P. Mendez-Samperio and colleagues from Mexico's National School of Biological Sciences wrote ("Down-Modulation of Mycobacterial-Induced IL-1(beta) Production in Human Mononuclear Cells by IL-4," Clinical Experimental Immunology, May 1996;104:374-379).
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