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Extrapulmonary Tuberculosis

Gen-Probe AMTD Test Useful With Many Specimen Types

Published in TB and Outbreaks Week, September 23rd, 1996

The Gen-Probe Amplified Mycobacterium tuberculosis Direct Test appears to perform equally well with many types of specimens, suggesting that it is useful for diagnosing extrapulmonary disease.

The diagnosis of extrapulmonary M. tuberculosis has posed a difficult challenge. Commercial nucleic acid amplification kits are licensed for use with respiratory specimens only, and experience with specimens of nonrespiratory origin is still limited. Although some investigators have reported preliminary sensitivities and specificities similar to those obtained when respiratory samples are tested, it has been demonstrated that, at least with some specimens like...

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