Diagnostics (TB)

PCR Critical in the Early Detection of TB Meningitis

Published in TB and Outbreaks Week, September 30th, 1996

Polymerase chain reaction is especially useful for the early diagnosis of tuberculous meningitis in those without active extraneural tuberculosis, according to a report from the Netherlands.

"We recommend that in cases of suspected tuberculous meningitis (TM), when results of microscopy are negative (the majority of the cases), treatment should be commenced and adequate volume of cerebrospinal fluid (greater than 2 mL) should be sent to a laboratory where polymerase chain reaction (PCR) can be rapidly performed," researcher Lan N. Nguyen and colleagues wrote ("The Potential Contribution of the PCR to the Diagnosis of Tuberculous Meningitis," Archives of Neurology,...

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Source: TB and Outbreaks Week (1996-09-30)

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