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Streptomycin Resistance Not Due to rpsL or rrs Mutations

Published in TB and Outbreaks Week, October 21st, 1996

Resistance to amikacin and streptomycin does not appear to occur from mutations in the "hot-spot" regions of the rpsL gene or the rrs gene, according to a report from Detroit, Michigan's Wayne State University.

The report was presented by researcher J. George and colleagues at the 36th meeting of the American Society for Microbiology's Interscience Conference on Antimicrobial Agents and Chemotherapy, held September 15-18, 1996 in New Orleans, Louisiana.

Streptomycin and other aminoglycosides such as amikacin (AMK) and kanamycin (KAN) are being used more and more frequently in the treatment of multidrug-resistant strains of...

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