"False-Positive Gen-Probe Direct M. tuberculosis Amplification Tests in Patients with Pulmonary M. kansasii Infection."

According to an abstract submitted by the authors to the 11th International Conference on AIDS, held July 7-12, 1996, in Vancouver, British Columbia, "The Gen-Probe transcription-mediated amplification test (MTD) has recently been approved for use in the U.S. for the rapid diagnosis of pulmonary tuberculosis in patients with acid-fast smear-positive sputum. Three HIV-infected patients seen in our institution with abnormal chest radiographs and fluorochrome stain-positive sputum were evaluated for tuberculosis, including performance of the MTD test on expectorated sputum samples. Two of three patients' sputa were highly smear-positive (i.e., >100 bacilli/high power field), while the...

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