"Comparison of the Ligase Chain Reaction Abbott LCx Probe System and the Polymerase Chain Reaction Roche Amplicor Test for Detection of Mycobacterium tuberculosis."

According to an abstract submitted by the authors to the 48th Annual Meeting of the American Association for Clinical Chemistry, held July 28 - August 1, 1996, in Chicago, Illinois, "The laboratory diagnosis of Mycobacterium tuberculosis (Mtb) in respiratory specimens is currently based on acid-fast staining and culture of decontaminated samples on solid media or radiometric liquid culture. Problems with these procedures include low sensitivity, lack of specificity with staining, or slow methodology. New diagnostic methods employing gene technology based on amplification and detection of bacterial ONA are expected to enhance Mycobacterium detection. The purpose of this...

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