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Diagnostics (TB)

"The Incidence of False-Positive Cultures for Mycobacterium tuberculosis."

Published in TB and Outbreaks Week, March 3rd, 1997

According to the authors' abstract of an article published in American Journal of Respiratory and Critical Care Medicine, "The frequency of false-positive cultures for Mycobacterium tuberculosis due to cross-contamination has been difficult to determine because of the lack of specific strain markers. Isolates collected prospectively over 5 yr from a municipal health department laboratory underwent DNA fingerprinting using the IS6110 and pTBN12 sequences. We reviewed the clinical and laboratory records of all isolates that had matching DNA fingerprints and were processed within 42 d of each other; 8 isolates were classified as probable or definite false-positives, representing 4.0%...

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