Pediatrics (TB)

Ethambutol Safe for Treating Children with TB

Published in TB and Outbreaks Week, May 5th, 1997

Ethambutol is a safe and effective antituberculosis agent in children that can be given to those aged five or older at a dosage of 15/mg/kg/day, according to a report from the International Union Against Tuberculosis and Lung Disease.

Ethambutol is the dextrorotatory isomer of the synthetic compound 2,2'-ethylenediimino-di-1-butanol dihydrochloride that has been used as an antituberculous agent since the 1960s. Other isomers were also initially used for this purpose but required higher dosages and were more toxic; ocular toxic complications were reported frequently.

"Although ethambutol has been regarded as a bacteriostatic agent, some studies...

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Source: TB and Outbreaks Week (1997-05-05)

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