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Legionella (Diagnostics)

"Rapid Diagnosis Of Legionella pneumophila Serogroup 1 Infection with the Binax Enzyme Immunoassay Urinary Antigen Test."

Published in TB and Outbreaks Week, May 12th, 1997

According to the authors' abstract of an article published in Journal of Clinical Microbiology, "The Binax legionella urinary antigen (LUA) enzyme immunoassay (Binax, Portland, Maine) was evaluated in 159 patients with suspected or proven legionellosis and 209 controls. A positive LUA test was found in 37% of patients with suspected legionellosis overall and in 83% of those with proven Legionella pneumophila serogroup 1 infection. The sensitivity of the LUA test was significantly greater than that of the direct fluorescent-antigen test (83 versus 42%; P<0.0001) but not significantly different from that of culture (85%) or serology (91%); specificity was at least 99.5%." ...

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