TB/HIV Coinfection
"Mycobacterium tuberculosis Enhances Human Immunodeficiency Virus-1 Replication in the Lung."
Published in TB and Outbreaks Week, May 12th, 1997
According to the authors' abstract of an article published in American Journal of Respiratory and Critical Care Medicine, "We investigated the in vivo effect of coinfection of Mycobacterium tuberculosis on human immunodeficiency virus type 1 (HIV-1) replication using bronchoalveolar lavage (BAL) of 11 HIV-1-infected patients with pulmonary tuberculosis and 10 patients with no lung disease. Lung segments involved with pulmonary tuberculosis had significantly elevated HIV-1 branched DNA (bDNA) levels and p24 in BAL compared with lung segments uninvolved with tuberculosis or with BAL from patients with no lung disease. The BAL viral burden was higher than plasma HIV-1 in tuberculosis...
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