"Comparison of Radioimmunoassay and Enzyme Immunoassay Kits for Detection of Legionella pneumophila Serogroup 1 Antigen in Both Concentrated and Nonconcentrated Urine Samples."

According to the authors' abstract of an article published in Journal of Clinical Microbiology, "We evaluated a commercial enzyme immunoassay (EIA) kit for detection of Legionella pneumophila serogroup 1 soluble antigen by comparing it to radioimmunoassay (RIA), using both concentrated and nonconcentrated urine samples. The sensitivity of EIA was 67.4% in nonconcentrated urine samples and 82.6% in concentrated urine samples. The sensitivity of RIA was 60.9% and 84.8% in nonconcentrated and concentrated urine samples, respectively. Our study indicates that the sensitivity and specificity of EIA are comparable to those of RIA, and that concentrating the antigen by selective...

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