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Measles

"Enzyme-Linked Immunosorbent Assay IgG Antibody Avidity Test for Single Sample Serologic Evaluation of Measles Vaccines."

Published in TB and Outbreaks Week, September 1st, 1997

According to the authors' abstract of an article published in Journal of Medical Virology, "A measles-specific enzyme-linked immunosorbent assay (ELISA)-IgG avidity test for serologic evaluation of the efficacy of measles vaccines with only one blood sample was evaluated after vaccination with three measles vaccine strains. Avidity indices were determined by the urea elution technique in samples presenting antibody titers greater than or equal to 100 mlU/ml. All 127 sera collected 2-8 weeks after primary vaccination with Biken-CAM70 measles vaccine had low avidity indices (LAI, when less than or equal to 29%) with a time-dependent increase in avidity. In samples collected 6-10 weeks...

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