Pharmacokinetics (TB)

HIV Infection Lowers Drug Concentrations

Published in TB and Outbreaks Week, September 15th, 1997

Tuberculosis patients with HIV infection exhibit lower plasma concentrations of rifampin and other antituberculosis drugs, according to a report from Canada.

Despite this finding, researcher Jan Sahai and colleagues do not recommend that prescribed doses of antituberculosis drugs be increased for patients infected with HIV.

"Studies of patients with active tuberculosis are urgently needed to determine the clinical and microbiological significance of our pharmacokinetic study and to evaluate therapeutic drug monitoring with dose adjustment before recommendations can be made," Sahai et al. wrote ("Reduced Plasma Concentrations of Antituberculosis Drugs...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of TB and Outbreaks Week

Source: TB and Outbreaks Week (1997-09-15)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry