Published in TB and Outbreaks Week, September 22nd, 1997
These various approaches create immunogenic chimeric molecules by combining T-cell antigens with self molecules.
"Viral peptides delivered by chimeric self molecules are more immunogenic than peptides alone and can induce a strong cellular immune response in vitro and in vivo," said Constatin A. Bona of the Mt. Sinai School of Medicine, New York.
Bona described the approach in an address to the first annual International Society for Vaccines Symposium on Vaccinology, held September 8-11, 1997, in...
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