Disease Indicators (TB)

Chest Findings Not Predictable in Newly Infected

Published in TB and Outbreaks Week, November 10th, 1997

Chest radiographic findings of mediastinal adenopathy and pleural effusion are not reliable indicators of tuberculosis from recent infection, according to a multicenter report.

Researcher Peter F. Barnes and colleagues further noted that upper lobe infiltrates and cavitation are not indicators of remote infection.

The only accepted method to confirm that recent infection is responsible for tuberculosis in an adult is documentation at the time of tuberculin skin test conversion. Because such information is rarely available, alternative strategies are needed.

One approach is to use restriction fragment length polymorphism (RFLP)...

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Source: TB and Outbreaks Week (1997-11-10)

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