Diagnosis (TB)

PCR Not Ideal for Spotting Pleural Tuberculosis

Published in TB and Outbreaks Week, February 2nd, 1998

Polymerase chain reaction analysis may be less sensitive than widely believed for the identification of pleural tuberculosis, according to a report from Spain.

Tuberculous pleural effusion (PE) usually occurs secondary to an immunologic reaction by the pleura to scant bacilli. The diagnosis of tuberculous PE is important because 60 percent to 65 percent of patients with this condition will develop some other form of active tuberculosis.

Acid-fast staining and cultures have traditionally been used to identify Mycobacterium tuberculosis in pleural fluid (PF) for the diagnosis of pleural tuberculosis, but both methods have serious...

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Source: TB and Outbreaks Week (1998-02-02)

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