Treatment Assessment (TB)

New Abscesses Don't Automatically Mean Treatment Failure

Published in TB and Outbreaks Week, February 2nd, 1998

The development of new lesions during tuberculosis chemotherapy may not necessarily imply treatment failure.

Researchers from the University of Florida report the case of a 23-year-old woman with miliary tuberculosis who experience worsening of her symptoms and subcutaneous abscesses four months after beginning appropriate antituberculous therapy.

The phenomenon of paradoxical expansion is characterized by a transient worsening of infection at a preexisting site or the development of new lesions during successful therapy. The condition is rare but has been reported among patients with tuberculosis involving the central nervous system, lymph nodes,...

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Source: TB and Outbreaks Week (1998-02-02)

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