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Case Reports

First Case of Amyloidosis Due to M. simiae Reported

Published in TB and Outbreaks Week, March 16th, 1998

Researchers in Israel describe a case of reactive amyloidosis due to chronic pulmonary infection with Mycobacterium simiae.

Although the elderly patient was given adequate antituberculosis drugs, he died due to low treatment compliance.

M. simiae was first isolated in 1965 from monkeys and in 1971 from man. Although usually not pathogenic in humans, it may cause pneumonia, pulmonary cavitary lesions and disseminated disease in elderly patients with chronic pulmonary disease and lung malignancy and in immunocompromised hosts.

Reactive amyloidosis is a disorder characterized by the deposition of amyloid A (AA) in...

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