Epidemiology (TB)

Differing TB Strains Hold Key to Spread of Disease

Published in TB and Outbreaks Week, April 6th, 1998

The evaluation of Mycobacterium tuberculosis strains that cause outbreaks in different geographic locations should provide insight into the epidemiological and bacteriological factors that facilitate the spread of tuberculosis.

The understanding of the dynamics of tuberculosis transmission has been greatly enhanced by the development of genotyping methods that allow identification of specific strains of M. tuberculosis. The most widely used genotyping method is DNA fingerprinting, based on restriction fragment length polymorphism (RFLP) analysis with the insertion element IS6110, which produces extensive fingerprint diversity among M. tuberculosis...

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Source: TB and Outbreaks Week (1998-04-06)

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