Published in TB and Outbreaks Week, April 6th, 1998
The understanding of the dynamics of tuberculosis transmission has been greatly enhanced by the development of genotyping methods that allow identification of specific strains of M. tuberculosis. The most widely used genotyping method is DNA fingerprinting, based on restriction fragment length polymorphism (RFLP) analysis with the insertion element IS6110, which produces extensive fingerprint diversity among M. tuberculosis...
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