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Drug Resistance

Eviction From Scum Home Makes Disease-Causing Microbe Vulnerable

Published in TB and Outbreaks Week, April 27th, 1998

A team of microbiologists has found a chink in the armor of an opportunistic microbe that is a top cause of infections in hospitals.

By genetically altering the bacterium Pseudomonas aeruginosa, the team was able to break up the colonies that normally make the organism resistant to detergents and antibiotics.

The work relies on mucking up the chemical communication system that the bacteria use to "talk" to each other when releasing toxins and gaining a foothold in humans, animals, and even plants.

The finding, by scientists at Montana State University, the University of Iowa, and the University of Rochester, was...

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