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Mycobacterial Disease (Conference News)

Gene Defect Linked to Susceptibility to Mycobacterium fortuitum Infection

Published in TB and Outbreaks Week, May 4th, 1998

Results of a new study showed that a gene defect confers susceptibility to mycobacterial infection.

The gene is found in the Interferon-(gamma) signaling chain (IFN(gamma)R2) - one of the two parts of the IFN(gamma) receptor in white blood cells. IFN(gamma), a protein produced by white blood cells, helps the immune system kill mycobacteria.

The study findings were presented by U.S. National Institutes of Health researchers S.E. Dorman and S.M. Holland at Biomedicine '98, the TriSocieties National Conference in Washington, D.C., held May 1-3, 1998. The TriSocieties comprises the American Federation for Medical Research, the American Society for...

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