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FbpA Protein Important in M. tb Survival/Growth

Published in TB and Outbreaks Week, June 8th, 1998

The fibronectin-binding protein FbpA appears to be important in the intracellular survival and growth of Mycobacterium tuberculosis, according to a report from the University of Texas Medical School.

The report was presented by researcher Lisa Armitige and colleagues at the 98th General Meeting of the American Society of Microbiology, held May 17-21, 1998 in Atlanta, Georgia.

The Antigen 85 Complex is a family of fibronectin-binding proteins consisting of three principle members: FbpA, FbpB, and FbpC. These proteins have mycolyl transferase activity and appear to be involved in the synthesis of the cell wall components trehalose monomycolate...

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