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Meningitis

"In vitro Antibiotic Synergy Against Flavobacterium meningosepticum: Implications for Therapeutic Options."

Published in TB and Outbreaks Week, June 29th, 1998

According to the authors' abstract of an article published in Clinical Infectious Diseases, "Flavobacterium meningosepticum is an unusual, highly resistant, Gram-negative bacillus that is associated with neonatal meningitis and nursery outbreaks of meningitis. The optimal therapy for this infection is not known. We successfully treated three neonates with intravenous vancomycin and rifampin. We determined the in vitro activity of meropenem, ciprofloxacin, vancomycin, linezolid (PNU-100766), and rifampin, alone and in combination, against four isolates of F. meningosepticum from neonates with sepsis and meningitis. MICs were determined by tube dilution, and fractional...

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