Pathogenesis (TB)
Mouse May be Key to Understanding Mycobacterial Infection
Published in TB and Outbreaks Week, June 29th, 1998
Tests with the model, developed by researchers at the Massachusetts Institute of Technology, suggest that interferon-gamma is important in the regulation of hematopoiesis only under conditions of stress.
"The results suggest that in the absence of interferon-gamma (IFN-gamma) and effective macrophage function, a pathologic granulocytic response is mounted in an attempt by the organism to combat mycobacterial infection," Peter J. Murray and colleagues wrote ("Hematopoietic Remodeling in...
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