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Therapeutic Monoclonal Antibody Approved for Respiratory Syncytial Virus Disease

Published in TB and Outbreaks Week, July 13th, 1998

The U.S. Food and Drug Administration (FDA) has approved a monoclonal antibody to protect high-risk infants against the worst effects of respiratory syncytial virus (RSV) disease, the most common cause of lower respiratory infections in children.

The product, palivizumab, is a genetically engineered antibody against the RSV virus. This antibody is manufactured using human and mouse antibody genes and can be produced consistently on a large scale.

Palivizumab is the second product licensed for RSV disease. The first one, RSV Immune Globulin Intravenous (Human) (RSVIGIV) is made from human plasma and is marketed as RespiGam by MedImmune Inc,...

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