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Tuberculosis (HIV Co-infection)

"Effect of Preventive Treatment for Tuberculosis in Adults Infected with HIV: Systematic Review of Randomised Placebo Controlled Trials."

Published in TB and Outbreaks Week, October 19th, 1998

According to the authors' abstract of an article published in British Medical Journal, "Objective: To determine whether preventive treatment for tuberculosis in adults infected with HIV reduces the frequency of tuberculosis and overall mortality. Design: Systematic review and data synthesis of randomised placebo controlled trials. Main Outcome Measures: Active tuberculosis, mortality, and adverse drug reaction requiring cessation of the study regimen. Outcomes stratified by status of purified protein derivative skin test. Results: Four trials comprising 4,055 adults from Haiti, Kenya, the United States, and Uganda were included. All compared...

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