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Testing (TB)

Gen-Probe Direct Test Sensitive in Detecting M. tuberculosis

Published in TB and Outbreaks Week, December 28th, 1998

A comparison of Mycobacterium tuberculosis detection methods finds a new gen-probe amplified direct test more sensitive than the semiautomated Abbott LCx assay when respiratory and extrapulmonary specimens are examined.

Two commercial assays that detect M. tuberculosis complex (MTB) in clinical specimens by rRNA target amplification (AMTDII) and ligase chain reaction (LCx) were evaluated. The tests were applied to 457 respiratory (n = 273) and extrapulmonary (n = 184) specimens collected from 357 patients ("Comparison Evaluation of the New Gen-Probe Mycobacterium tuberculosis Amplified Direct Test and the Semiautomated Abbott LCx Mycobacterium...

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