"Instability of Tuberculin and Candida Skin Test Reactivity in HIV Infected Ugandans."

According to the authors' abstract of an article published in American Journal of Respiratory and Critical Care Medicine, "Anergy testing has been used as an adjunct to tuberculin testing for assessing M. tuberculosis (MTB) infection and indications for isoniazid preventive therapy in HIV infected persons. We examined factors associated with the stability of skin test responses to purified protein derivative (PPD) and Candida antigens in a cohort of HIV infected adults followed prospectively in a tuberculosis preventive therapy trial in Uganda. PPD-positive and anergic subjects in the placebo arms of the preventive therapy study underwent repeat skin testing and immunologic...

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