Testing (TB)

PCR Adequately Detects M. tuberculosis in Sputum

Published in TB and Outbreaks Week, February 8th, 1999

Polymerase chain reaction is useful in diagnosing tuberculosis in induced sputum, according to a report from Japan.

The polymerase chain reaction (PCR) technique was compared with the conventional smear and culture method for the detection and identification of Mycobacterium tuberculosis in 25 induced sputa samples ("Diagnosis of Pulmonary Tuberculosis by the Amplicor Test for Mycobacterium tuberculosis in Induced Sputum," Nihon Kokyuki Gakkai Zasshi, November 1998;36(11):959-962).

Sputum induction was performed with an ultrasonic nebulizer using 3 percent hypertonic saline in 27 previously untreated patients suspected of active...

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Source: TB and Outbreaks Week (1999-02-08)

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