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Therapy (TB)

Rifampin Monoresistance Usually Seen in HIV+

Published in TB and Outbreaks Week, February 22nd, 1999

Rifampin monoresistance is primarily seen in people with a history of prior tuberculosis who are HIV positive, according to a case-control study from New York University.

Rifampin is the cornerstone of short-course chemotherapy for the treatment of tuberculosis (TB). Rifampin monoresistance (RMR) is less common than resistance to isoniazid alone or resistance to more than one antituberculosis agent.

In this study, L. Sandman and colleagues conducted a retrospective case-control study to identify risk factors for RMR-TB ("Risk Factors for Rifampin-Monoresistant Tuberculosis: A Case-Control Study," American Journal of Respiratory and Critical Care...

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