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Antiretroviral Therapy May Prompt Clinical MAC

Published in TB and Outbreaks Week, March 1st, 1999

Combination antiretroviral therapy may "unmask" subclinical Mycobacterium avium complex (MAC) disease, according to a report from the University of British Columbia.

To characterize the impact of combination antiretroviral therapy on the clinical and laboratory features of mycobacterial lymphadenitis, researcher P. Phillips and colleagues conducted a retrospective chart review of HIV related mycobacterial lymphadenitis at Vancouver's St. Paul's hospital between 1989 and 1997 ("Mycobacterial Lymphadenitis Associated with the Initiation of Combination Antiretroviral Therapy," Journal of AIDS and Human Retrovirology, February 1999;20(2):122-128).

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